Buy Lincocin Online

Lincomycin is an antibiotic approved for use in veterinary medicine only in Germany. It is particularly effective against gram-positive bacteria. It is also approved for the treatment of humans in the United States and Canada.

What is Lincocin?

Lincomycin (chemical formula: C18H34N2O6S) is a drug belonging to the class of antibiotics. In Germany, Lincocin is only approved in veterinary medicine. In the United States, however, the substance is also used in humans.

Lincomycin is one of the lincosamides, which are all antibiotics. The molar mass of the substance is 406.54 g / mol. The drug is obtained by isolating the bacteria Streptomyces lincolnensis.

From a chemical point of view, Lincocin is composed of propylproline and aminosugar methylthiolincosamide, which are linked by an amide bond. Lincomycin hydrochloride monohydrate is normally used for medicinal purposes. Lincocin is particularly effective against gram-positive bacteria.

Lincomycin is in the form of a white to off-white crystalline powder and has a weak odor. The drug is soluble in water. Overall, the fabric is slightly basic. The solution for injection is colorless to pale yellow and the melting point of the hydrochloride monohydrate is approximately 145 to 147 degrees Celsius. That of monohydrochloride at around 155 to 157 degrees Celsius.

Pharmacological effects on the body and organs

The spectrum of action and mode of action is the same as that of clindamycin, which is also approved for use in humans in Germany. However, it is less powerful.

As with macrolides, Lincocin works by inhibiting protein biosynthesis by binding to the 50-S subunit of bacterial ribosomes.

Gram-positive pathogens are particularly sensitive to lincomycin. For this reason, the substance is, for example, effective against streptococci and staphylococci. Depending on the dosage and sensitivity of the pathogen, the effect of the substance is either bacteriostatic or bactericidal.

The active substance accumulates in the macrophages, the "phagocytes" of the immune system and is transported with them to the place of action. Lincocin is metabolized exclusively in the liver. The substance is excreted by the faeces.

The CSF does not reach a sufficient concentration to have an effect.

Medical application and use for treatment and prevention

When considering its medical use, it is first visible that lincomycin is not approved for use in humans in Germany. In human medicine, the substance is not used in Germany. In the United States, however, Lincocin is also used in human medicine.

It can be said that the substance covers the same spectrum of activity as the macrolides and the substance clindamycin, which also belongs to the group of lincosamides, but is less potent than clindamycin and less tolerated than the representatives of macrolides.

In veterinary medicine, lincomycin is used against all bacteria sensitive to the active ingredient. In general, it is used for various bacterial infections of domestic and livestock animals, the efficacy of which is best for respiratory infections. Lincocin is an antibiotic commonly prescribed in veterinary medicine.

Here you will find your medication

Risks and side effects

The type of application of lincomycin is of great importance. It should not be administered orally to herbivores, as this can cause fatal side effects. For this reason, horses, ruminants, guinea pigs, rabbits and hamsters can only be administered parenterally with Lincocin. If these animals are administered orally, fatal inflammation of the colon may result from clostridia resistant to lincomycin.

If Lincocin is administered intramuscularly, painful swelling may occur at the injection site. When given intravenously, it should be noted that if done too quickly, it can cause thrombophlebitis, low blood pressure and cardiac arrest.

When administered orally, gastrointestinal inflammation with vomiting and bloody diarrhea may occur.

In case of hypersensitivity to the active ingredient, it should not be administered.

Lincomycin is not approved for the treatment of humans in Germany.