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Article about Furacin

Pharmacological properties

Pharmacodynamics

Antimicrobial agent from the group of nitrofuran derivatives. It has a bacteriostatic effect on gram-positive and gram-negative bacteria (staphylococci, streptococci, Escherichia coli, Proteus, Salmonella, Escherichia), as well as Trichomonas and Giardia.

Antibiotic and sulfonamide resistant microorganisms are sensitive to furacilin. Resistance to furacilin develops slowly and does not reach a high degree.

Pharmacokinetics

With local and external use, absorption is negligible. If swallowed, absorption is rapid and complete. Penetrates through histohematological barriers and is distributed evenly in fluids and tissues.

The time required to reach the maximum concentration is 6 hours. The main route of metabolism is the restoration of the nitro group. It is excreted by the kidneys and partially by the intestines.

Directions for use

  • purulent infected wounds, bedsores, ulcers;
  • infected burns of degrees II and III;
  • preparation of the granulation surface for skin grafts;
  • osteomyelitis;
  • empyema of the pleura;
  • boiling of the external auditory canal;
  • sinus empyema;
  • conjunctivitis.
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Dosage and administration

With purulent wounds, bedsores, ulcers, burns of degrees II and III, to prepare the granulation surface for skin transplants and secondary suture, the wound is irrigated with an aqueous solution of furatsilin and wet dressings are applied.

In osteomyelitis, after the operation, the cavity is washed with an aqueous solution of furatsilin and a wet dressing is applied. With empyema, the pleura is aspirated with pus, the pleural cavity is washed, followed by the introduction of 20 to 100 ml of an aqueous solution of furatsilin in the cavity.

In the treatment of boils in the external auditory canal and empyema of the paranasal sinuses, the damaged areas are washed 2 to 4 to 6 times a day (depending on the severity of the damage).

In the treatment of conjunctivitis - instillation of an aqueous solution into the conjunctival sac 2-3 drops 3-4 times a day.

The duration of treatment is determined by the doctor, taking into account the characteristics of the disease, tolerance to drugs and the effect obtained.

Side effect

For external use, furatsilin is generally well tolerated. In some cases, dermatitis is possible, requiring a temporary break or stopping the medication. Bleeding.

In case of undesirable effects, including those not specified in this instruction, you should stop using the drug and consult a doctor.

Cons-indications

  • severe renal failure;
  • allergic dermatoses;
  • hypersensitivity to nitrofuran derivatives.

Overdose

Subject to the recommended methods of use, cases of overdose are not known. With random ingestion, the development of nausea, vomiting, loss of appetite, dizziness, neuritis is possible.

Safety precautions

Due to the lack of safety data, the drug is not recommended for children and adolescents under 18 years of age.

When using the drug, so-called cross-awareness is possible. To avoid sensitization, it is recommended to use the drug for no more than 5 days.

If, while using the drug, symptoms of the disease persist or the condition worsens, it is necessary to stop the use of the drug and consult a doctor.

Pregnancy and breast feeding

When prescribing to pregnant women, breastfeeding women and children, it is recommended to consider the possible risk and benefits of using this medication.

Impact on ability to drive potentially dangerous vehicles and machinery

No effects on the ability to drive potentially dangerous vehicles and machinery have been observed.

Interaction with other drugs

Incompatible with epinephrine (adrenaline), tetracaine, procaine (novocaine), resorcinol (resorcinol) and other reducing agents, as it decomposes with the formation of pink or brownish products.

Incompatible with potassium permanganate, hydrogen peroxide and other oxidizing agents due to oxidation of the drug.

Storage conditions

Keep in a dark place at a temperature not exceeding 77 °F. Keep out of reach of children.

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